High-Tech gem Thermo Fisher Scientific unveils the tiniest details of life in Brabant

Setting up Titan Krios electron microscope at the New York Structural Biology Center (NYSBC).
For over 75 years, state-of-the-art electron microscopes are being developed in Eindhoven. Originally as a spin-off from Philips, now as a part of the American multinational Thermo Fisher Scientific. Thermo Fisher demonstrates commitment to expanding in Brabant, embracing an innovative future.
20 September 2024
Setting up Titan Krios electron microscope at the New York Structural Biology Center (NYSBC).

Groundbreaking electron microscopes

Located on Business Park Acht in Eindhoven, Thermo Fisher’s facility is a center of excellence for electron microscopy. Here, over 1,300 dedicated professionals with 46 different nationalities work collaboratively to create groundbreaking and reliable solutions in electron microscopy. The facility is also a hub for novel research applications of electron microscopes and provides service and support to users.

Thermo Fisher is an important global innovator in electron microscopy. Maurits Smits, Senior Director in Eindhoven, explains: “Bringing technical breakthroughs to the world is our daily goal and challenge. Our technology gives researchers eyes in places previously unthinkable. Our technology allows researchers to explore molecular structures, down to the scale of a picometer – much smaller than a nanometer. This capability enables them to make informed decisions to make the world healthier, cleaner and safer. Working on solutions to global challenges is incredibly fulfilling. Our microscopes are used by several Nobel laureates, and their feedback has driven further advancements in our technology.”

Philips began developing and marketing electron microscopes in 1949, initially under the name Philips Electron Optics. FEI Company started selling sources in 1971. In 1997, a collaboration with the American company FEI, known for its expertise in electron and ion sources and columns, led to a takeover. The newly formed Dutch branch, FEI Electron Optics BV, continued the legacy. In 2016, Thermo Fisher acquired FEI because they saw great potential in electron microscopes. For example, in areas like life sciences, accelerating advancements in structural biology, and material sciences, due to its increasing demands in for instance nanotechnology. By acquiring FEI, Thermo Fisher created an even stronger position in these fields, recognizing its complementary portfolio..

Today, the American multinational has over $40 billion in annual sales and more than 125,000 employees worldwide. While the company’s overall product and service range is broad, the Eindhoven facility remains focused on electron microscopy.

From my office, I can see a neighboring Philips building, a reminder of our heritage. The historic Philips’ knowledge and technology influences the entire region intertwining various companies within the local ecosystem, including ASML’s semiconductor equipment or some medical implants. The Brainport region now brings together world-class experts in technology, manufacturing, and academia, fostering collaboration and accelerating technological development

Maurits Smits, Senior Director, Thermo Fisher Scientific Eindhoven

Exploring boundless applications

The versatility of electron microscopes extends across various fields. According to Maurits: “Our microscopes enable the study of atomic structures in materials like silicon and gallium, crucial for the semiconductor industry. For example, they can reveal atomic structures in lithium batteries, aiding in their durability and safety. In the world of life sciences, scientists are looking deeper and deeper into the cells of animals, humans and plants. Researchers use our microscopes to explore cellular structures and understand complex medical questions, such as why certain drugs work for some individuals but not others. Right now, we help to enable research on Alzheimer’s disease, among other medical conditions. And during the COVID-19 pandemic, the initial images of the coronavirus proteins were captured using our electron microscopes. We can really make a difference for humanity.”

Making waves

Maurits embraces high-tech companies in the region, viewing them as a catalysts for innovation. “We always thought we had to adapt, learn to surf the waves that other companies were making. Now we know that we are making waves ourselves. The synergy among companies here propels us forward and in turn, we play a significant role in pushing other business forward as well. I always call it a perpetuum mobile: once it starts, it keeps improving as long as it’s well-maintained. In the Brainport region, we have a lot of talent and knowledge. That has a pulling effect on companies and people who want to work with and for highly innovative companies like Thermo Fisher.”

“Thermo Fisher is a leading company in Brabant, yet its impact is not very well known or widely recognized by the general public. Its contributions are significant on regional, national, and international levels.”

Mike Houtkamp, Project Manager Foreign Investments, Brabant Development Agency (BOM)

Thermo Fisher was not always aware of its role in the ecosystem. Mike Houtkamp, Project Manager for Foreign Investments at the Brabant Development Agency (BOM), observes: “Thermo Fisher is a leading company in Brabant, yet its impact is not very well known or widely recognized by the general public. Its contributions are significant on regional, national, and international levels.”

Maurits agrees: “We’ve often been focused on our work, without paying much attention to the positive impact we make. In 2022, we decided to share our story more broadly. Within our ecosystem and beyond. By partnering up with organizations such as BOM, the Ministry of Economic Affairs, and RVO, together we aim to encourage growth and innovation in our field.”

Solid growth ambitions

Thermo Fisher has ambitious plans for expansion in Eindhoven. In 2021, the company acquired an adjacent building, adding 1,100 square meters to boost production by twenty percent. Maurits explains: “Expanding involves many aspects, like obtaining permits and ensuring adequate electricity supply. The latter is important, as we are committed to achieving net-zero carbon emissions by 2050. Additionally, grid congestion is a challenge in the Netherlands, potentially limiting our ability to grow. We have therefore actively looked for innovative solutions to meet our energy needs in a sustainable way. BOM has been instrumental in this process, offering expertise on smart energy solutions and connecting us with valuable contacts. We are now pursuing various alternatives: generating our own power, implementing battery storage, and collaborating with other companies at the Business Park Acht to optimize energy supply and demand among companies. We also reduce our own energy consumption by making our microscopes more energy efficient. In this way we are not only innovative in our product offering, but in every aspect of what we do. In our new building, for instance, we have started production without additional power requirements. In fact, energy challenges foster creativity and innovation.”

Bright future

Maurits emphasizes the importance of having the company’s long term commitment in addressing proper energy management: “I’m glad Thermo Fisher is committed to net-zero emissions by 2050, enabling us to take a proactive, long-term approach to sustainable and adequate energy management. A partner like BOM, who offers extensive knowledge in local energy management and technological innovation, simplifies the implementation process and supports relevant interactions with the government and business community.”

Thermo Fisher continues its vital work in Eindhoven, contributing to the ecosystem and exploring further growth possibilities. What’s next? The company now aims to maximize the utilization of the remaining space in its new building as quickly as possible. And many more exciting developments lie ahead!

Want to learn more?

Our sector specialist

Mike Houtkamp

Project Manager Foreign Investments Life Sciences & Health, UK, Nordics